SCIENTISTS FOUND ANTI-TUMOR POTENTIAL IN CBC AND CBG CANNABINOIDS
An investigation that Cannabics Pharmaceuticals conducted recently found that cannabinoids called Cannabichromene, better known as CBC, and Cannabigerol have anti-tumor properties.
Research conducted at high-performance screening facilities found that these cannabis molecules may be helpful in fighting gastrointestinal cancer and its side effects. Besides, cannabis molecules inhibits tumor.
These cannabinoids are part of the 113 Phyto-cannabinoids that cannabis contains. These elements originate from organic compounds in the plant.
In addition, it should be noted that, to date, not enough research has been done on the effects that CBC and CBG have on other conditions, so researchers are urged to carry out more practices with these molecules.
In the case of CBC, it should be noted that it is a non-psychoactive cannabinoid, which has a large number of therapeutic qualities, such as having anti-inflammatory, antimicrobial, analgesic as well as neurogenesis action.
This molecule is generally found in very low concentrations, particularly in newer cannabis plants. According to recent research, when combined with THC and CBD, it could also have antidepressant properties along with treating tumor.
For its part, cannabigerol or CBG is a Phyto-cannabinoid found naturally in hemp and is usually at relatively low levels in other marijuana varieties.
The Sensiseeds portal mentions a medical research on glaucoma – the results showed that CBG is able to reduce intraocular pressure and increase water flow in the tissue surrounding the feline’s eye.
Later, other research conducted with rodents revealed that CBG has an effect to relief vomiting and nausea, in addition to reducing intestinal inflammation and colitis in these animals.
Furthermore, other studies have analyzed that this molecule reduces pain, relieves psoriasis and its symptoms, has antibacterial action and also slows down the spread of tumor cells.
Because of this, Cannabics Pharmaceuticals used high-performance tests to detect the necrotic effects that are found in various cannabinoids on the cancer cells in human gastrointestinal system, in addition to other previously tested cancers.
CBC and CBG vs Gastric cancer
The result was that both molecules produced significantly higher rates of necrosis. Necrosis means the cancer cell death in gastric cancer patients compared to the results they obtained using other cannabinoids.
For the head of cannabidiol research at the research firm who led the research, these results show that there is a correlation between the value of the topological polar surface area (TPSA) of these cannabinoids and their ability to reduce viability of tumor activity in a cell. This property helps to fight against tumor and gradually vanish it away.
This is because CBC and CBG are neutral cannabinoids, with a TPSA value that allows their compounds to penetrate the membrane of a cancer cell. On the other hand, acidic cannabinoids (CBCA and CBGA) cannot perform this action.
For this group of scientists, this discovery could mean a health alternative for dozens of patients around the world, who every year lose their lives due to gastric cancer.